Old St. Vincent Church, built in 1853, is located at the corner of William and Main Sts. in Cape Girardeau, Missouri 63701.

If you are traveling north or south on I-55, exit the Interstate at the Route K/William St. exit, and proceed east toward the Mississippi River.

If you are approaching Cape Girardeau from the Illinois side of the Mississippi River, cross the Bill Emerson Memorial Bridge heading west. The church is in view as you cross the bridge. Turn right at the Fountain St. exit (1st right turn), take a right turn on Morgan Oak St. and a left turn onto Spanish St. Proceed two blocks north when you will see the back of our beautiful church at Spanish & William Sts.

Welcome to Old St. Vincent Church.